AMDA: Study Suggests Frailty As a Predictor of Readmission and Mortality in Heart Failure

November 19, 2018

COLUMBIA, Maryland, Nov. 15 AMDA - The Society for Post-Acute and Long-Term Care Medicine issued the following news release:

Frailty in the elderly has long been associated with an increased risk of falls, functional limitations, hospitalizations, and death. Now a new study in the November issue of JAMDA shows frailty as a significant predictor of all-cause mortality and hospital readmissions in patients with heart failure.

In "Frailty and Clinical Outcomes in Heart Failure: A Systematic Review and Meta-analysis," the authors analyzed studies in the PubMed and Embase databases that involved patients with a definite diagnosis of heart failure and frailty that was quantified and related to the primary endpoints of all-cause mortality or hospitalization. The analysis demonstrated a 1.59-fold increase in the risk of all-cause mortality for frail patients, compared with non-frail patients. Additionally, they observed a significantly higher risk of hospital readmissions between the frail and non-frail patients. The study also suggested that patients with frailty, compared to non-frail patients, had a significantly increased risk of all-cause mortality after undergoing ventricular assist device (VAD) implantation.